The BACE1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to BACE1. This antibody recognizes Mouse, and Rat antigen. The BACE1 Rabbit mAb Antibody has been validated for the following applications: Western Blot.
Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type